NCRR primarily utilizes data from numerous Danish registers to investigate long-term causes and outcomes of severe mental disorders. This work has documented several key factors within psychiatric epidemiology, including urban birth, paternal age, psychiatric family history, lifetime risk, infections, neonatal vitamin D deficiency, socio-economic adversity, treatment resistant schizophrenia and pharmalogical treatment, and many more.
However, researchers at NCRR also conduct projects that shine light on other important public areas. For example, they are involved in register-based projects investigating health consequences of air pollution, connection between school, education and social mobility, connection between lifestyle and health issues such as cancer, and many others.
Moreover, the new-established iPSYCH2012 sample enables researchers to provide a continuous measure of reliability, which greatly enhances the possibility to combine genetic, environmental and phenotypic data in a broad range of studies. Since the initiation of the iPSYCH2012 sample, many related Danish projects are built on the same framework as projects within iPSYCH. This includes disorders like anorexia, obsessive-compulsive disorder, conduct disorder, and hyperkinetic conduct disorder.
For further Reading:
Zerwas S, et al (2017): Eating Disorders, Autoimmune, and Autoinflammatory Disease. Pediatrics 10.1542/peds.2016-2089
Pedersen CB et al. (2017): The iPSYCH2012 case-cohort sample: new directions for unraveling genetic and environmental architectures of severe mental disorders. Molecular Psychiatry: http://rdcu.be/zk9N
Mohr-Jensen C, et al (2016). The validity and reliability of the diagnosis of hyperkinetic disorders in the Danish Psychiatric Central Research Registry. European Psychiatry http://dx.doi.org/10.1016/j.eurpsy.2016.01.2427
Zerwas S et al. (2015): The incidence of eating disorders in a Danish register study: Associations with suicide risk and mortality. Journal of Psychiatric Research: http://dx.doi.org/10.1016/j.jpsychires.2015.03.003
Sorensen CJ et al (2014): Combined oral contraception and obesity are strong predictors of low-grade inflammation in healthy individuals: results from the Danish Blood Donor Study (DBDS). PLos One: https://doi.org/10.1371/journal.pone.0088196
Tjonneland A, et al. (2007): Study design, exposure variables, and socioeconomic determinants of participation in Diet, Cancer and Health: a population-based prospective cohort study of 57,053 men and women in Denmark. Scand J Public Health: https://doi.org/10.1080/14034940601047986